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Postdoctoral Research Associate in Molecular Imaging

Employer
KINGS COLLEGE LONDON
Location
London (Greater) (GB)
Salary
£44,355 - £51,735 per annum including London Weighting Allowance
Closing date
4 Jun 2025
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Job Details

About Us

The Faculty of Life Sciences & Medicine is one of the largest and most successful centres for research and education in the UK. The Faculty was created as a result of the merger of elements of the School of Biomedical Sciences with the School of Medicine. The merger brings together basic, translational and clinical scientists to provide new cross-School research collaborations while optimising the deployment of teaching expertise across the Faculty. The Faculty has unparalleled expertise in basic, translational and clinical research in: analytical and forensic science; asthma and allergy; biophysics and cell biology; cancer; cardiovascular; nutrition and diabetes; genetics; infection and immunology; imaging and biomedical engineering; transplantation immunology; pharmaceutical science; physiology and women's health. We also have thriving research programmes in global health, and health and social care. Further information about the Faculty of Life Sciences and Medicine may be found at https://www.kcl.ac.uk/lsm/index.aspx 

Within FoLSM, the School of Biomedical Engineering and Imaging Sciences is a cutting-edge research and teaching School dedicated to development, translation and clinical application within medical imaging and computational modelling technologies. Our objective is to facilitate research and teaching guided by clinical questions and is aimed at novelty, understanding of physiology and pathophysiology as well as development of new diagnostic tools and therapies. In this way, basic science can be rapidly translated into clinical applications (and vice versa). The School consists of eight research departments: Cardiovascular Imaging, Cancer Imaging, Early Life Imaging, Imaging Chemistry & Biology, Biomedical Computing, Surgical & Interventional Engineering, Imaging Physics & Engineering and Digital Twins for Healthcare. 

The Research Department of Imaging Chemistry and Biology comprises a group of ca. 50 scientific and clinical researchers who drive translational radiopharmaceutical development, theragnostics, nanotechnology, metallomics, immuno-imaging, metabolic imaging, functional cardiac imaging, radiobiology, and engineering solutions for GMP radiopharmaceutical production. Embedding highly innovative scientists alongside clinical staff in a hospital environment has offered an unparalleled opportunity for translational impact that is being realised across the world-leading research infrastructure.

About The Role

The role is to synthesise and assess novel radiopharmaceuticals and multi-modal probes and provide expertise as a lead chemist in a multi-disciplinary team of chemists, radiochemists, (radio)biologists, preclinical molecular imaging scientists. Particular expertise is required in synthetic chemistry to design novel target structures suitable for labelling procedures.

The post holder will join the department of Imaging Chemistry & Biology and the CARL (Cyclotron and Radiochemistry Laboratory) facility with the specific role of designing and synthesising novel radiopharmaceuticals/multi-modal probes and perform radiolabelling research with established and novel radionuclides, including 18F, 124I, 68Ga, 161Tb, 64/67Cu, 203/212Pb, 211At.

Hence, we are looking for a talented and self-motivated scientist with a strong expertise in organic/organometallic chemistry and probe design to perform imaging probe development for future clinical translation. The post holder will work collaboratively with research groups externally, including industrial partners. 

The post holder will be expected not only to perform projects within their specified remit but also to provide training, assistance and advice to other workers and collaborators. 

The role may be a basis for first-author publications on the development of preclinical imaging methodology in this field as well as co-authoring user-led publications. 

This is a full-time post (35 hours per week) and you will be offered a fixed term contract of 24 months from start date.

About You

To be successful in this role, we are looking for candidates to have the following skills and experience: 

Essential criteria 

  1. PhD level qualified in chemistry, radiochemistry (or relevant chemistry field) at or near completion 
  2. Advanced knowledge in targeted (multi-modal) probe development. 
  3. Expertise in development and optimisation of organic/organometallic synthesis methodology. 
  4. Advanced skills in study/experimental design and analysis of complex research data. 
  5. Basic knowledge of preclinical (in vitro and/or in vivo) validation. 
  6. Expertise in bioconjugation techniques (peptides, antibodies) 
  7. Excellent inter-personal skills with an ability to work co-operatively in a multidisciplinary setting, working closely with biologists, chemists, radiochemists and GMP radiopharmaceutical production facility. 
  8. Possess excellent written and verbal communication skills and maintain accurate and up-to-date records of all findings, and to make these available to other members of the team.

Desirable criteria 

  1. Advanced knowledge in the use of analytical spectroscopy techniques. 
  2. Basic knowledge of one or more aspects of radiochemical synthesis (radiometal chelation, organic isotope labelling etc.) and/or photophysical molecular imaging properties. 
  3. Knowledge in the design of imaging probe validation experiments using a combination of in vivo, in vitro and analytical methods.

Downloading a copy of our Job Description

Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the next page after you click “Apply Now”. This document will provide information of what criteria will be assessed at each stage of the recruitment process.

Further Information

We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community. We are committed to working with our staff and unions on these and other issues, to continue to support our people and to develop a diverse and inclusive culture at King's.

We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible. 

To find out how our managers will review your application, please take a look at our ‘How we Recruit’ pages. Interviews are due to be held on 6th June 2025.

Grade and Salary: £44,355 - £51,735 per annum including London Weighting Allowance
Job ID: 115625
Close Date: 04-Jun-2025
Contact Person: Stephen Archibald
Contact Details: stephen.archibald@kcl.ac.uk

Company

King's College London is one of the top 20 universities in the world and among the oldest in England. King's has more than 27,600 students (of whom nearly 10,500 are graduate students) from some 150 countries worldwide, and some 6,800 staff.

King's has an outstanding reputation for world-class teaching and cutting-edge research. In the 2014 Research Excellence Framework (REF) King’s was ranked 6th nationally in the ‘power’ ranking, which takes into account both the quality and quantity of research activity, and 7th for quality according to Times Higher Education rankings. Eighty-four per cent of research at King’s was deemed ‘world-leading’ or ‘internationally excellent’ (3* and 4*). The university is in the top seven UK universities for research earnings and has an overall annual income of more than £684 million.

King's has a particularly distinguished reputation in the humanities, law, the sciences (including a wide range of health areas such as psychiatry, medicine, nursing and dentistry) and social sciences including international affairs. It has played a major role in many of the advances that have shaped modern life, such as the discovery of the structure of DNA and research that led to the development of radio, television, mobile phones and radar.

King's College London and Guy's and St Thomas', King's College Hospital and South London and Maudsley NHS Foundation Trusts are part of King's Health Partners. King's Health Partners Academic Health Sciences Centre (AHSC) is a pioneering global collaboration between one of the world's leading research-led universities and three of London's most successful NHS Foundation Trusts, including leading teaching hospitals and comprehensive mental health services. For more information, visit: www.kingshealthpartners.org.

King’s £600 million campaign, World questions|KING’s answers, has delivered huge global impact in areas where King’s has particular expertise. Philanthropic support has funded new research to save young lives at Evelina London Children’s Hospital; established the King’s Dickson Poon School of Law as a worldwide leader in transnational law; built a new Cancer Centre at Guy’s Hospital; allowed unique collaboration between leading neuroscientists to fast-track new treatments for Alzheimer’s, Parkinson’s, motor neurone disease, depression and schizophrenia at the new Maurice Wohl Clinical Neuroscience Institute; created the Cicely Saunders Institute: the first academic institution in the world dedicated to palliative care, and supported the King’s Sierra Leone Partnership in the Ebola crisis. Donations provide over 300 of the most promising students with scholarships and bursaries each year. More information about the campaign is available at www.kcl.ac.uk/kingsanswers.

Company info
Mini-site
KINGS COLLEGE LONDON
Telephone
+(44)02078365454
Location
STRAND
LONDON
WC2R 2LS
GB

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